RING-box protein 2 (RNF7)

About RING-box protein 2

RING-box protein 2 (RNF7) is a protein from Homo sapiens identified by UniProt accession Q9UBF6, 113 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.

Target properties

Protein name	RING-box protein 2
UniProt accession	Q9UBF6
Gene	RNF7
Organism	Homo sapiens
Length	113 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (54)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.33
susceptibility to Mycobacterium tuberculosis infection measurement · score 0.16
tuberculosis · score 0.16
cirrhosis of liver · score 0.13
hepatitis C virus infection · score 0.13
neoplasm · score 0.09
pachyonychia congenita · score 0.07
nonpapillary renal cell carcinoma · score 0.07
adolescent idiopathic scoliosis · score 0.06
erythrocyte count · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UBF6-F1	alphafold	PREDICTED	81.73	—

Amino-acid sequence (113 residues)

MADVEDGEET CALASHSGSS GSKSGGDKMF SLKKWNAVAM WSWDVECDTC AICRVQVMDA CLRCQAENKQ EDCVVVWGEC NHSFHNCCMS LWVKQNNRCP LCQQDWVVQR IGK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards