Stomatin-like protein 1 (STOML1)

About Stomatin-like protein 1

Stomatin-like protein 1 (STOML1) is a protein from Homo sapiens identified by UniProt accession Q9UBI4, 398 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

Target properties

Protein name	Stomatin-like protein 1
UniProt accession	Q9UBI4
Gene	STOML1
Organism	Homo sapiens
Length	398 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (41)

Diseases linked to this target (Open Targets).

body mass index · score 0.38
angina pectoris · score 0.30
SAPHO syndrome · score 0.21
insomnia · score 0.19
peak expiratory flow · score 0.19
insomnia measurement · score 0.16
type 2 diabetes mellitus · score 0.15
BMI-adjusted waist-hip ratio · score 0.14
pathological myopia · score 0.13
physical activity measurement · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UBI4-F1	alphafold	PREDICTED	74.68	—

Amino-acid sequence (398 residues)

MLGRSGYRAL PLGDFDRFQQ SSFGFLGSQK GCLSPERGGV GTGADVPQSW PSCLCHGLIS FLGFLLLLVT FPISGWFALK IVPTYERMIV FRLGRIRTPQ GPGMVLLLPF IDSFQRVDLR TRAFNVPPCK LASKDGAVLS VGADVQFRIW DPVLSVMTVK DLNTATRMTA QNAMTKALLK RPLREIQMEK LKISDQLLLE INDVTRAWGL EVDRVELAVE AVLQPPQDSP AGPNLDSTLQ QLALHFLGGS MNSMAGGAPS PGPADTVEMV SEVEPPAPQV GARSSPKQPL AEGLLTALQP FLSEALVSQV GACYQFNVVL PSGTQSAYFL DLTTGRGRVG HGVPDGIPDV VVEMAEADLR ALLCRELRPL GAYMSGRLKV KGDLAMAMKL EAVLRALK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards