Protein UXT (UXT)

About Protein UXT

Protein UXT (UXT) is a protein from Homo sapiens identified by UniProt accession Q9UBK9, 157 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

Target properties

Protein name	Protein UXT
UniProt accession	Q9UBK9
Gene	UXT
Organism	Homo sapiens
Length	157 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (44)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.44
lysosomal storage disease · score 0.33
nonpapillary renal cell carcinoma · score 0.06
neoplasm · score 0.05
cancer · score 0.04
cryopyrin-associated periodic syndrome · score 0.03
retinitis pigmentosa · score 0.03
benign prostatic hyperplasia · score 0.03
gonorrhea · score 0.02
pachyonychia congenita · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UBK9-F1	alphafold	PREDICTED	88.04	—

Amino-acid sequence (157 residues)

MATPPKRRAV EATGEKVLRY ETFISDVLQR DLRKVLDHRD KVYEQLAKYL QLRNVIERLQ EAKHSELYMQ VDLGCNFFVD TVVPDTSRIY VALGYGFFLE LTLAEALKFI DRKSSLLTEL SNSLTKDSMN IKAHIHMLLE GLRELQGLQN FPEKPHH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards