About Opticin
Opticin (OPTC) is a protein
from Homo sapiens identified by UniProt accession
Q9UBM4, 332 residues long.
MolForge cross-references it against 0 known binders and
54 disease associations.
Target properties
| Protein name | Opticin |
|---|
| UniProt accession | Q9UBM4 |
|---|
| Gene | OPTC |
|---|
| Organism | Homo sapiens |
|---|
| Length | 332 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (54)
Diseases linked to this target (Open Targets).
- body mass index · score 0.39
- body fat percentage · score 0.33
- type 2 diabetes mellitus · score 0.32
- sex hormone-binding globulin measurement · score 0.32
- triglyceride measurement · score 0.32
- BMI-adjusted waist-hip ratio · score 0.30
- hip circumference · score 0.30
- BMI-adjusted hip circumference · score 0.29
- high density lipoprotein cholesterol measurement · score 0.28
- diabetes mellitus · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UBM4-F1 | alphafold | PREDICTED | 74.28 | — |
Amino-acid sequence (332 residues)
MRLLAFLSLL ALVLQETGTA SLPRKERKRR EEQMPREGDS FEVLPLRNDV LNPDNYGEVI DLSNYEELTD YGDQLPEVKV TSLAPATSIS PAKSTTAPGT PSSNPTMTRP TTAGLLLSSQ PNHGLPTCLV CVCLGSSVYC DDIDLEDIPP LPRRTAYLYA RFNRISRIRA EDFKGLTKLK RIDLSNNLIS SIDNDAFRLL HALQDLILPE NQLEALPVLP SGIEFLDVRL NRLQSSGIQP AAFRAMEKLQ FLYLSDNLLD SIPGPLPLSL RSVHLQNNLI ETMQRDVFCD PEEHKHTRRQ LEDIRLDGNP INLSLFPSAY FCLPRLPIGR FT
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