Cathepsin Z (CTSZ)

About Cathepsin Z

Cathepsin Z (CTSZ) is a protein from Homo sapiens identified by UniProt accession Q9UBR2, 303 residues long. MolForge cross-references it against 0 known binders and 194 disease associations.

Target properties

Protein name	Cathepsin Z
UniProt accession	Q9UBR2
Gene	CTSZ
Organism	Homo sapiens
Length	303 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UBR2-F1	alphafold	PREDICTED	92.02	—

Amino-acid sequence (303 residues)

MARRGPGWRP LLLLVLLAGA AQGGLYFRRG QTCYRPLRGD GLAPLGRSTY PRPHEYLSPA DLPKSWDWRN VDGVNYASIT RNQHIPQYCG SCWAHASTSA MADRINIKRK GAWPSTLLSV QNVIDCGNAG SCEGGNDLSV WDYAHQHGIP DETCNNYQAK DQECDKFNQC GTCNEFKECH AIRNYTLWRV GDYGSLSGRE KMMAEIYANG PISCGIMATE RLANYTGGIY AEYQDTTYIN HVVSVAGWGI SDGTEYWIVR NSWGEPWGER GWLRIVTSTY KDGKGARYNL AIEEHCTFGD PIV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards