About Protein FAM8A1
Protein FAM8A1 (FAM8A1) is a protein
from Homo sapiens identified by UniProt accession
Q9UBU6, 413 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Protein FAM8A1 |
|---|
| UniProt accession | Q9UBU6 |
|---|
| Gene | FAM8A1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 413 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- mental or behavioural disorder · score 0.06
- attention deficit hyperactivity disorder · score 0.05
- schizophrenia 15 · score 0.04
- pulmonary arterial hypertension · score 0.01
- COVID-19 · score 0.00
- schizophrenia · score 0.00
- meningococcal infection · score 0.00
- ulcerative colitis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UBU6-F1 | alphafold | PREDICTED | 58.30 | — |
Amino-acid sequence (413 residues)
MAEGPEEARG HPPGQDDGGG DHEPVPSLRG PPTTAVPCPR DDPQAEPQAP GRPTAPGLAA AAAADKLEPP RELRKRGEAA SGSGAELQEQ AGCEAPEAAA PRERPARLSA REYSRQVHEW LWQSYCGYLT WHSGLAAFPA YCSPQPSPQS FPSGGAAVPQ AAAPPPPQLG YYNPFYFLSP GAAGPDPRTA AGISTPAPVA GLGPRAPHVQ ASVRATPVTR VGSAAPSRSP SETGRQAGRE YVIPSLAHRF MAEMVDFFIL FFIKATIVLS IMHLSGIKDI SKFAMHYIIE EIDEDTSMED LQKMMVVALI YRLLVCFYEI ICIWGAGGAT PGKFLLGLRV VTCDTSVLIA PSRVLVIPSS NVSITTSTIR ALIKNFSIAS FFPAFITLLF FQHNRTAYDI VAGTIVVKRN GVR
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