Mortality factor 4-like protein 1 (MORF4L1)

About Mortality factor 4-like protein 1

Mortality factor 4-like protein 1 (MORF4L1) is a protein from Homo sapiens identified by UniProt accession Q9UBU8, 362 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Mortality factor 4-like protein 1
UniProt accession	Q9UBU8
Gene	MORF4L1
Organism	Homo sapiens
Length	362 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

coronary artery disease · score 0.38
pulse pressure measurement · score 0.37
myocardial infarction · score 0.36
serum alanine aminotransferase measurement · score 0.25
breast adenocarcinoma · score 0.22
Red cell distribution width · score 0.21
angina pectoris · score 0.17
Myocardial Ischemia · score 0.12
heart disease · score 0.09
diastolic blood pressure · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UBU8-F1	alphafold	PREDICTED	73.00	—

Amino-acid sequence (362 residues)

MAPKQDPKPK FQEGERVLCF HGPLLYEAKC VKVAIKDKQV KYFIHYSGWN KKSAVRPRRS EKSLKTHEDI VALFPVPEGA PSVHHPLLTS SWDEWVPESR VLKYVDTNLQ KQRELQKANQ EQYAEGKMRG AAPGKKTSGL QQKNVEVKTK KNKQKTPGNG DGGSTSETPQ PPRKKRARVD PTVENEETFM NRVEVKVKIP EELKPWLVDD WDLITRQKQL FYLPAKKNVD SILEDYANYK KSRGNTDNKE YAVNEVVAGI KEYFNVMLGT QLLYKFERPQ YAEILADHPD APMSQVYGAP HLLRLFVRIG AMLAYTPLDE KSLALLLNYL HDFLKYLAKN SATLFSASDY EVAPPEYHRK AV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards