About Protein Wnt-16
Protein Wnt-16 (WNT16) is a protein
from Homo sapiens identified by UniProt accession
Q9UBV4, 365 residues long.
MolForge cross-references it against 0 known binders and
135 disease associations.
Target properties
| Protein name | Protein Wnt-16 |
|---|
| UniProt accession | Q9UBV4 |
|---|
| Gene | WNT16 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 365 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (135)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.55
- bone density · score 0.49
- bone quantitative ultrasound measurement · score 0.47
- osteoporosis · score 0.42
- bone fracture · score 0.39
- FEV/FVC ratio · score 0.37
- wrist fracture · score 0.34
- cortical thickness · score 0.32
- spine bone mineral density · score 0.32
- bone disease · score 0.30
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UBV4-F1 | alphafold | PREDICTED | 88.29 | — |
Amino-acid sequence (365 residues)
MDRAALLGLA RLCALWAALL VLFPYGAQGN WMWLGIASFG VPEKLGCANL PLNSRQKELC KRKPYLLPSI REGARLGIQE CGSQFRHERW NCMITAAATT APMGASPLFG YELSSGTKET AFIYAVMAAG LVHSVTRSCS AGNMTECSCD TTLQNGGSAS EGWHWGGCSD DVQYGMWFSR KFLDFPIGNT TGKENKVLLA MNLHNNEAGR QAVAKLMSVD CRCHGVSGSC AVKTCWKTMS SFEKIGHLLK DKYENSIQIS DKTKRKMRRR EKDQRKIPIH KDDLLYVNKS PNYCVEDKKL GIPGTQGREC NRTSEGADGC NLLCCGRGYN THVVRHVERC ECKFIWCCYV RCRRCESMTD VHTCK
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