Beta-1,4-galactosyltransferase 7 (B4GALT7)

About Beta-1,4-galactosyltransferase 7

Beta-1,4-galactosyltransferase 7 (B4GALT7) is a protein from Homo sapiens identified by UniProt accession Q9UBV7, 327 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

Target properties

Protein name	Beta-1,4-galactosyltransferase 7
UniProt accession	Q9UBV7
Gene	B4GALT7
Organism	Homo sapiens
Length	327 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (44)

Diseases linked to this target (Open Targets).

Ehlers-Danlos syndrome, progeroid type · score 0.79
Ehlers-Danlos syndrome, spondylodysplastic type · score 0.70
Ehlers-Danlos syndrome · score 0.42
genetic disorder · score 0.41
Skeletal dysplasia · score 0.37
Larsen-like syndrome, B3GAT3 type · score 0.26
leukocyte count · score 0.15
mathematical ability · score 0.11
self reported educational attainment · score 0.09
hepatocellular carcinoma · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UBV7-F1	alphafold	PREDICTED	87.95	—

Amino-acid sequence (327 residues)

MFPSRRKAAQ LPWEDGRSGL LSGGLPRKCS VFHLFVACLS LGFFSLLWLQ LSCSGDVARA VRGQGQETSG PPRACPPEPP PEHWEEDASW GPHRLAVLVP FRERFEELLV FVPHMRRFLS RKKIRHHIYV LNQVDHFRFN RAALINVGFL ESSNSTDYIA MHDVDLLPLN EELDYGFPEA GPFHVASPEL HPLYHYKTYV GGILLLSKQH YRLCNGMSNR FWGWGREDDE FYRRIKGAGL QLFRPSGITT GYKTFRHLHD PAWRKRDQKR IAAQKQEQFK VDREGGLNTV KYHVASRTAL SVGGAPCTVL NIMLDCDKTA TPWCTFS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards