About Peflin
Peflin (PEF1) is a protein
from Homo sapiens identified by UniProt accession
Q9UBV8, 284 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | Peflin |
|---|
| UniProt accession | Q9UBV8 |
|---|
| Gene | PEF1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 284 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (24)
Diseases linked to this target (Open Targets).
- cognitive function measurement · score 0.16
- intelligence · score 0.16
- self reported educational attainment · score 0.13
- lean body mass · score 0.11
- body mass index · score 0.11
- body height · score 0.10
- appendicular lean mass · score 0.09
- fat body mass · score 0.08
- FEV/FVC ratio · score 0.08
- verbal-numerical reasoning measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UBV8-F1 | alphafold | PREDICTED | 73.31 | — |
Amino-acid sequence (284 residues)
MASYPYRQGC PGAAGQAPGA PPGSYYPGPP NSGGQYGSGL PPGGGYGGPA PGGPYGPPAG GGPYGHPNPG MFPSGTPGGP YGGAAPGGPY GQPPPSSYGA QQPGLYGQGG APPNVDPEAY SWFQSVDSDH SGYISMKELK QALVNCNWSS FNDETCLMMI NMFDKTKSGR IDVYGFSALW KFIQQWKNLF QQYDRDRSGS ISYTELQQAL SQMGYNLSPQ FTQLLVSRYC PRSANPAMQL DRFIQVCTQL QVLTEAFREK DTAVQGNIRL SFEDFVTMTA SRML
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