Beta-1,4-galactosyltransferase 6 (B4GALT6)

About Beta-1,4-galactosyltransferase 6

Beta-1,4-galactosyltransferase 6 (B4GALT6) is a protein from Homo sapiens identified by UniProt accession Q9UBX8, 382 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	Beta-1,4-galactosyltransferase 6
UniProt accession	Q9UBX8
Gene	B4GALT6
Organism	Homo sapiens
Length	382 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (38)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.43
TNF-related apoptosis-inducing ligand measurement · score 0.33
pancreatic adenocarcinoma · score 0.21
glioblastoma multiforme · score 0.14
vitamin A measurement · score 0.05
cystic fibrosis · score 0.02
lung carcinoma · score 0.02
thyroxine measurement · score 0.02
astrocytoma · score 0.01
Friedreich ataxia · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UBX8-F1	alphafold	PREDICTED	88.81	—

Amino-acid sequence (382 residues)

MSVLRRMMRV SNRSLLAFIF FFSLSSSCLY FIYVAPGIAN TYLFMVQARG IMLRENVKTI GHMIRLYTNK NSTLNGTDYP EGNNSSDYLV QTTTYLPENF TYSPYLPCPE KLPYMRGFLN VNVSEVSFDE IHQLFSKDLD IEPGGHWRPK DCKPRWKVAV LIPFRNRHEH LPIFFLHLIP MLQKQRLEFA FYVIEQTGTQ PFNRAMLFNV GFKEAMKDSV WDCVIFHDVD HLPENDRNYY GCGEMPRHFA AKLDKYMYIL PYKEFFGGVS GLTVEQFRKI NGFPNAFWGW GGEDDDLWNR VHYAGYNVTR PEGDLGKYKS IPHHHRGEVQ FLGRYKLLRY SKERQYIDGL NNLIYRPKIL VDRLYTNISV NLMPELAPIE DY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards