About Heat shock protein beta-7
Heat shock protein beta-7 (HSPB7) is a protein
from Homo sapiens identified by UniProt accession
Q9UBY9, 170 residues long.
MolForge cross-references it against 0 known binders and
139 disease associations.
Target properties
| Protein name | Heat shock protein beta-7 |
|---|
| UniProt accession | Q9UBY9 |
|---|
| Gene | HSPB7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 170 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (139)
Diseases linked to this target (Open Targets).
- hypertrophic cardiomyopathy · score 0.28
- electrocardiography · score 0.25
- body height · score 0.24
- systolic blood pressure · score 0.24
- diastolic blood pressure · score 0.21
- left ventricular ejection fraction measurement · score 0.18
- breast carcinoma · score 0.17
- ovarian carcinoma · score 0.17
- prostate carcinoma · score 0.17
- sitting height measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UBY9-F1 | alphafold | PREDICTED | 73.31 | — |
Amino-acid sequence (170 residues)
MSHRTSSTFR AERSFHSSSS SSSSSTSSSA SRALPAQDPP MEKALSMFSD DFGSFMRPHS EPLAFPARPG GAGNIKTLGD AYEFAVDVRD FSPEDIIVTT SNNHIEVRAE KLAADGTVMN TFAHKCQLPE DVDPTSVTSA LREDGSLTIR ARRHPHTEHV QQTFRTEIKI
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