Zinc finger protein 70 (ZNF70)

About Zinc finger protein 70

Zinc finger protein 70 (ZNF70) is a protein from Homo sapiens identified by UniProt accession Q9UC06, 446 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	Zinc finger protein 70
UniProt accession	Q9UC06
Gene	ZNF70
Organism	Homo sapiens
Length	446 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (11)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.27
sex hormone-binding globulin measurement · score 0.04
IGF-1 measurement · score 0.02
lymphocyte count · score 0.02
leukocyte count · score 0.02
neoplasm · score 0.01
esophageal squamous cell carcinoma · score 0.01
colitis · score 0.01
Miyoshi myopathy · score 0.00
cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UC06-F1	alphafold	PREDICTED	71.51	—

Amino-acid sequence (446 residues)

MEVPPATKFG ETFAFENRLE SQQGLFPGED LGDPFLQERG LEQMAVIYKE IPLGEQDEEN DDYEGNFSLC SSPVQHQSIP PGTRPQDDEL FGQTFLQKSD LSMCQIIHSE EPSPCDCAET DRGDSGPNAP HRTPQPAKPY ACRECGKAFS QSSHLLRHLV IHTGEKPYEC CECGKAFSQS SHLLRHQIIH TGEKPYECRE CGKAFRQSSA LTQHQKIHTG KRPYECRECG KDFSRSSSLR KHERIHTGER PYQCKECGKS FNQSSGLSQH RKIHTLKKPH ECDLCGKAFC HRSHLIRHQR IHTGKKPYKC DECGKAFSQS SNLIEHRKTH TGEKPYKCQK CGKAFSQSSS LIEHQRIHTG EKPYECCQCG KAFCHSSALI QHQRIHTGKK PYTCECGKAF RHRSALIEHY KTHTREKPYV CNLCGKSFRG SSHLIRHQKI HSGEKL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards