About Protein phosphatase 1 regulatory subunit 1B
Protein phosphatase 1 regulatory subunit 1B (PPP1R1B) is a protein
from Homo sapiens identified by UniProt accession
Q9UD71, 204 residues long.
MolForge cross-references it against 0 known binders and
170 disease associations.
Target properties
| Protein name | Protein phosphatase 1 regulatory subunit 1B |
|---|
| UniProt accession | Q9UD71 |
|---|
| Gene | PPP1R1B |
|---|
| Organism | Homo sapiens |
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| Length | 204 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (170)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- erythrocyte count · score 0.27
- hematocrit · score 0.17
- self reported educational attainment · score 0.11
- neoplasm · score 0.10
- refractive error · score 0.10
- high density lipoprotein cholesterol measurement · score 0.10
- non-small cell lung carcinoma · score 0.10
- schizophrenia · score 0.09
- alcohol consumption measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UD71-F1 | alphafold | PREDICTED | 65.20 | — |
Amino-acid sequence (204 residues)
MDPKDRKKIQ FSVPAPPSQL DPRQVEMIRR RRPTPAMLFR LSEHSSPEEE ASPHQRASGE GHHLKSKRPN PCAYTPPSLK AVQRIAESHL QSISNLNENQ ASEEEDELGE LRELGYPREE DEEEEEDDEE EEEEEDSQAE VLKVIRQSAG QKTTCGQGLE GPWERPPPLD ESERDGGSED QVEDPALSEP GEEPQRPSPS EPGT
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