Zinc finger protein 212 (ZNF212)

About Zinc finger protein 212

Zinc finger protein 212 (ZNF212) is a protein from Homo sapiens identified by UniProt accession Q9UDV6, 495 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	Zinc finger protein 212
UniProt accession	Q9UDV6
Gene	ZNF212
Organism	Homo sapiens
Length	495 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

basophil percentage of granulocytes · score 0.22
basophil percentage of leukocytes · score 0.17
heel bone mineral density · score 0.15
neutrophil count · score 0.14
birth weight · score 0.13
monocyte percentage of leukocytes · score 0.08
Autosomal recessive cerebellar ataxia - psychomotor retardation · score 0.05
Rare hereditary ataxia · score 0.05
Dysequilibrium syndrome · score 0.05
Spinocerebellar ataxia type 41 · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UDV6-F1	alphafold	PREDICTED	53.91	—

Amino-acid sequence (495 residues)

MAESAPARHR RKRRSTPLTS STLPSQATEK SSYFQTTEIS LWTVVAAIQA VEKKMESQAA RLQSLEGRTG TAEKKLADCE KMAVEFGNQL EGKWAVLGTL LQEYGLLQRR LENVENLLRN RNFWILRLPP GSKGEAPKVS RSLENDGVCF TEQEWENLED WQKELYRNVM ESNYETLVSL KVLGQTEGEA ELGTEMLGDL EEEGPGGAHP AGGVMIKQEL QYTQEGPADL PGEFSCIAEE QAFLSPEQTE LWGGQGSSVL LETGPGDSTL EEPVGSRVPS SSRTVGCPKQ KSHRQVQLDQ ECGQGLKLKK DTSRPYECSE CEITFRYKQQ LATHLRSHSG WGSCTPEEPE ESLRPRPRLK PQTKKAKLHQ CDVCLRSFSC KVSLVTHQRC HLQEGPSAGQ HVQERFSPNS LVALPGHIPW RKSRSSLICG YCGKSFSHPS DLVRHQRIHT GERPYSCTEC EKSFVQKQHL LQHQKIHQRE RGGLALEPGR PNGLL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards