About Zinc finger matrin-type protein 5
Zinc finger matrin-type protein 5 (ZMAT5) is a protein
from Homo sapiens identified by UniProt accession
Q9UDW3, 170 residues long.
MolForge cross-references it against 0 known binders and
62 disease associations.
Target properties
| Protein name | Zinc finger matrin-type protein 5 |
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| UniProt accession | Q9UDW3 |
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| Gene | ZMAT5 |
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| Organism | Homo sapiens |
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| Length | 170 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (62)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- ulcerative colitis · score 0.13
- mean corpuscular hemoglobin concentration · score 0.12
- inflammatory bowel disease · score 0.09
- Crohn's disease · score 0.09
- aspartate aminotransferase measurement · score 0.07
- FEV/FVC ratio · score 0.07
- lean body mass · score 0.06
- self reported educational attainment · score 0.06
- pulse pressure measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UDW3-F1 | alphafold | PREDICTED | 83.98 | — |
Amino-acid sequence (170 residues)
MGKRYFCDYC DRSFQDNLHN RKKHLNGLQH LKAKKVWYDM FRDAAAILLD EQNKRPCRKF LLTGQCDFGS NCRFSHMSER DLQELSIQVE EERRAREWLL DAPELPEGHL EDWLEKRAKR LSSAPSSRAE PIRTTVFQYP VGWPPVQELP PSLRAPPPGG WPLQPRVQWG
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