SEC14-like protein 4 (SEC14L4)

About SEC14-like protein 4

SEC14-like protein 4 (SEC14L4) is a protein from Homo sapiens identified by UniProt accession Q9UDX3, 406 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.

Target properties

Protein name	SEC14-like protein 4
UniProt accession	Q9UDX3
Gene	SEC14L4
Organism	Homo sapiens
Length	406 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (36)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.43
Red cell distribution width · score 0.40
HbA1c measurement · score 0.38
apolipoprotein A 1 measurement · score 0.38
reticulocyte count · score 0.36
reticulocyte measurement · score 0.36
high density lipoprotein cholesterol measurement · score 0.35
hemolysis · score 0.25
lysosomal storage disease · score 0.09
Alzheimer disease · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UDX3-F1	alphafold	PREDICTED	95.21	—

Amino-acid sequence (406 residues)

MSSRVGDLSP QQQEALARFR ENLQDLLPIL PNADDYFLLR WLRARNFDLQ KSEDMLRRHM EFRKQQDLDN IVTWQPPEVI QLYDSGGLCG YDYEGCPVYF NIIGSLDPKG LLLSASKQDM IRKRIKVCEL LLHECELQTQ KLGRKIEMAL MVFDMEGLSL KHLWKPAVEV YQQFFSILEA NYPETLKNLI VIRAPKLFPV AFNLVKSFMS EETRRKIVIL GDNWKQELTK FISPDQLPVE FGGTMTDPDG NPKCLTKINY GGEVPKSYYL CEQVRLQYEH TRSVGRGSSL QVENEILFPG CVLRWQFASD GGDIGFGVFL KTKMGEQQSA REMTEVLPSQ RYNAHMVPED GSLTCLQAGV YVLRFDNTYS RMHAKKLSYT VEVLLPDKAS EETLQSLKAM RPSPTQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards