SEC14-like protein 3 (SEC14L3)

About SEC14-like protein 3

SEC14-like protein 3 (SEC14L3) is a protein from Homo sapiens identified by UniProt accession Q9UDX4, 400 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	SEC14-like protein 3
UniProt accession	Q9UDX4
Gene	SEC14L3
Organism	Homo sapiens
Length	400 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.21
high density lipoprotein cholesterol measurement · score 0.10
immune system disease · score 0.05
reticulocyte count · score 0.04
Red cell distribution width · score 0.04
reticulocyte measurement · score 0.04
hepatocellular carcinoma · score 0.03
HbA1c measurement · score 0.03
apolipoprotein A 1 measurement · score 0.03
lung adenocarcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UDX4-F1	alphafold	PREDICTED	96.91	—

Amino-acid sequence (400 residues)

MSGRVGDLSP KQAETLAKFR ENVQDVLPAL PNPDDYFLLR WLRARNFDLQ KSEALLRKYM EFRKTMDIDH ILDWQPPEVI QKYMPGGLCG YDRDGCPVWY DIIGPLDPKG LLFSVTKQDL LKTKMRDCER ILHECDLQTE RLGKKIETIV MIFDCEGLGL KHFWKPLVEV YQEFFGLLEE NYPETLKFML IVKATKLFPV GYNLMKPFLS EDTRRKIIVL GNNWKEGLLK LISPEELPAQ FGGTLTDPDG NPKCLTKINY GGEIPKSMYV RDQVKTQYEH SVQINRGSSH QVEYEILFPG CVLRWQFSSD GADIGFGVFL KTKMGERQRA GEMTDVLPSQ RYNAHMVPED GNLTCSEAGV YVLRFDNTYS FVHAKKVSFT VEVLLPDEGM QKYDKELTPV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards