Mitochondrial fission process protein 1 (MTFP1)

About Mitochondrial fission process protein 1

Mitochondrial fission process protein 1 (MTFP1) is a protein from Homo sapiens identified by UniProt accession Q9UDX5, 166 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.

Target properties

Protein name	Mitochondrial fission process protein 1
UniProt accession	Q9UDX5
Gene	MTFP1
Organism	Homo sapiens
Length	166 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (34)

Diseases linked to this target (Open Targets).

immune system disease · score 0.19
neoplasm · score 0.09
hepatocellular carcinoma · score 0.08
high density lipoprotein cholesterol measurement · score 0.05
cancer · score 0.04
oral squamous cell carcinoma · score 0.03
squamous cell lung carcinoma · score 0.02
calcium measurement · score 0.02
pulse pressure measurement · score 0.02
sarcoidosis · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UDX5-F1	alphafold	PREDICTED	86.77	—

Amino-acid sequence (166 residues)

MSEPQPRGAE RDLYRDTWVR YLGYANEVGE AFRSLVPAAV VWLSYGVASS YVLADAIDKG KKAGEVPSPE AGRSARVTVA VVDTFVWQAL ASVAIPGFTI NRVCAASLYV LGTATRWPLA VRKWTTTALG LLTIPIIIHP IDRSVDFLLD SSLRKLYPTV GKPSSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards