About RIMS-binding protein 3A
RIMS-binding protein 3A (RIMBP3) is a protein
from Homo sapiens identified by UniProt accession
Q9UFD9, 1639 residues long.
MolForge cross-references it against 0 known binders and
103 disease associations.
Target properties
| Protein name | RIMS-binding protein 3A |
|---|
| UniProt accession | Q9UFD9 |
|---|
| Gene | RIMBP3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 1639 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (103)
Diseases linked to this target (Open Targets).
- azoospermia · score 0.10
- male infertility with teratozoospermia due to single gene mutation · score 0.09
- partial chromosome Y deletion · score 0.08
- congenital bilateral absence of vas deferens · score 0.07
- spermatogenic failure 20 · score 0.07
- spermatogenic failure, X-linked, 3 · score 0.07
- spermatogenic failure 40 · score 0.07
- spermatogenic failure 10 · score 0.07
- spermatogenic failure 11 · score 0.07
- spermatogenic failure 47 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UFD9-F1 | alphafold | PREDICTED | 57.52 | — |
Amino-acid sequence (1639 residues)
MAKDSPSPLG ASPKKPGCSS PAAAVLENQR RELEKLRAEL EAERAGWRAE RRRFAARERQ LREEAERERR QLADRLRSKW EAQRSRELRQ LQEEMQRERE AEIRQLLRWK EAEQRQLQQL LHRERDGVVR QARELQRQLA EELVNRGHCS RPGASEVSAA QCRCRLQEVL AQLRWQTDGE QAARIRYLQA ALEVERQLFL KYILAHFRGH PALSGSPDPQ AVHSLEEPLP QTSSGSCHAP KPACQLGSLD SLSAEVGVRS RSLGLVSSAC SSSPDGLLST HASSLDCFAP ACSRSLDSTR SLPKASKSEE RPSSPDTSTP GSRRLSPPPS PLPPPPPPSA HRKLSNPRGG EGSESQPCEV LTPSPPGLGH HELIKLNWLL AKALWVLARR CYTLQAENKQ LRRAGCPYQA DEKVKRLKVK RAELTGLARR LADRARKLQE TNLRAVSAPI PGESCAGLEL CQVFARQRAR DLSEQASAPL AKDKQIEELR QECHLLQARV ASGPCSDLHT GRGGPCTQWL NVRDLDRLQR ESQREVLRLQ RQLMLQQGNG GAWPEAGGQS ATCEEVRRQM LALERELDQR RRECQELGAQ AAPARRRGEE AETQLQAALL KNAWLAEENG RLQAKTDWVR KVEAENSEVR GHLGRACQER DASGLIAEQL LQQAARGQDR QQQLQRDPQK ALCDLHPSWK EIQALQCRPG HPPEQPWETS QMPESQVKGS RRPKFHARPE DYAVSQPNRD IQEKREASLE ESPVALGESA SVPQVSETVP ASQPLSKKTS SQSNSSSEGS MWATVPSSPT LDRDTASEVD DLEPDSVSLA LEMGGSAAPA APKLKIFMAQ YNYNPFEGPN DHPEGELPLT AGDYIYIFGD MDEDGFYEGE LEDGRRGLVP SNFVEQIPDS YIPGCLPAKS PDLGPSQLPA GQDEALEEDS LLSGKAQGVV DRGLCQMVRV GSKTEVATEI LDTKTEACQL GLLQSMGKQG LSRPLLGTKG VLRMAPMQLH LQNVTATSAN ITWVYSSHRH PHVVYLDDRE HALTPAGVSC YTFQGLCPGT HYRARVEVRL PRDLLQVYWG TMSSTVTFDT LLAGPPYPPL DVLVERHASP GVLVVSWLPV TIDSAGSSNG VQVTGYAVYA DGLKVCEVAD ATAGSTLLEF SQLQVPLTWQ KVSVRTMSLC GESLDSVPAQ IPEDFFMCHR WPETPPFSYT CGDPSTYRVT FPVCPQKLSL APPSAKASPH NPGSCGEPQA KFLEAFFEEP PRRQSPVSNL GSEGECPSSG AGSQAQELAE AWEGCRKDLL FQKSPQNHRP PSVSDQPGEK ENCSQHMGTS KSPAPGFIHL RTECGPRKEP CQEKAALERV LRQKQDAQGF TPPQLGASQQ YASDFHNVLK EEQEALCLDL WGTERREERR EPEPHSRQGQ ALGVKRGCQL HEPSSALCPA PSAKVIKMPR GGPQQLGTGA NTPARVFVAL SDYNPLVMSA NLKAAEEELV FQKRQLLRVW GSQDTHDFYL SECNRQVGNI PGRLVAEMEV GTEQTDRRWR SPAQGNLPSV AHLEDFQGLT IPQGSSLVLQ GNSKRLPLWT PKIMIAALDY DPGDGQMGGQ GKGRLALRAG DVVMVYGPMD DQGFYYGELG GHRGLVPAHL LDHMSLHGH
Explore RIMS-binding protein 3A with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets