CCR4-NOT transcription complex subunit 8 (CNOT8)

About CCR4-NOT transcription complex subunit 8

CCR4-NOT transcription complex subunit 8 (CNOT8) is a protein from Homo sapiens identified by UniProt accession Q9UFF9, 292 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

Target properties

Protein name	CCR4-NOT transcription complex subunit 8
UniProt accession	Q9UFF9
Gene	CNOT8
Organism	Homo sapiens
Length	292 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UFF9-F1	alphafold	PREDICTED	90.01	—

Amino-acid sequence (292 residues)

MPAALVENSQ VICEVWASNL EEEMRKIREI VLSYSYIAMD TEFPGVVVRP IGEFRSSIDY QYQLLRCNVD LLKIIQLGLT FTNEKGEYPS GINTWQFNFK FNLTEDMYSQ DSIDLLANSG LQFQKHEEEG IDTLHFAELL MTSGVVLCDN VKWLSFHSGY DFGYMVKLLT DSRLPEEEHE FFHILNLFFP SIYDVKYLMK SCKNLKGGLQ EVADQLDLQR IGRQHQAGSD SLLTGMAFFR MKELFFEDSI DDAKYCGRLY GLGTGVAQKQ NEDVDSAQEK MSILAIINNM QQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards