About Regulator of G-protein signaling 17
Regulator of G-protein signaling 17 (RGS17) is a protein
from Homo sapiens identified by UniProt accession
Q9UGC6, 210 residues long.
MolForge cross-references it against 0 known binders and
61 disease associations.
Target properties
| Protein name | Regulator of G-protein signaling 17 |
|---|
| UniProt accession | Q9UGC6 |
|---|
| Gene | RGS17 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 210 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (61)
Diseases linked to this target (Open Targets).
- body mass index · score 0.50
- glucose measurement · score 0.47
- prostate carcinoma · score 0.47
- high density lipoprotein cholesterol measurement · score 0.46
- type 2 diabetes mellitus · score 0.45
- BMI-adjusted waist-hip ratio · score 0.43
- IGF-1 measurement · score 0.42
- mathematical ability · score 0.42
- HbA1c measurement · score 0.42
- body height · score 0.39
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UGC6-F1 | alphafold | PREDICTED | 78.60 | — |
Amino-acid sequence (210 residues)
MRKRQQSQNE GTPAVSQAPG NQRPNNTCCF CWCCCCSCSC LTVRNEERGE NAGRPTHTTK MESIQVLEEC QNPTAEEVLS WSQNFDKMMK APAGRNLFRE FLRTEYSEEN LLFWLACEDL KKEQNKKVIE EKARMIYEDY ISILSPKEVS LDSRVREVIN RNLLDPNPHM YEDAQLQIYT LMHRDSFPRF LNSQIYKSFV ESTAGSSSES
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