About Olfactory receptor 14J1
Olfactory receptor 14J1 (OR14J1) is a protein
from Homo sapiens identified by UniProt accession
Q9UGF5, 321 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Olfactory receptor 14J1 |
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| UniProt accession | Q9UGF5 |
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| Gene | OR14J1 |
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| Organism | Homo sapiens |
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| Length | 321 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (16)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.33
- neuroblastoma · score 0.21
- risk-taking behaviour · score 0.19
- ovarian cancer · score 0.18
- mathematical ability · score 0.17
- multiple myeloma · score 0.16
- MHC class I polypeptide-related sequence B measurement · score 0.16
- refractive error · score 0.12
- age at onset · score 0.12
- Myopia · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UGF5-F1 | alphafold | PREDICTED | 87.62 | — |
Amino-acid sequence (321 residues)
MVNLTSMSGF LLMGFSDERK LQILHALVFL VTYLLALTGN LLIITIITVD RRLHSPMYYF LKHLSLLDLC FISVTVPQSI ANSLMGNGYI SLVQCILQVF FFIALASSEV AILTVMSYDR YAAICQPLHY ETIMDPRACR HAVIAVWIAG GLSGLMHAAI NFSIPLCGKR VIHQFFCDVP QMLKLACSYE FINEIALAAF TTSAAFICLI SIVLSYIRIF STVLRIPSAE GRTKVFSTCL PHLFVATFFL SAAGFEFLRL PSDSSSTVDL VFSVFYTVIP PTLNPVIYSL RNDSMKAALR KMLSKEELPQ RKMCLKAMFK L
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