Olfactory receptor 12D3 (OR12D3)

About Olfactory receptor 12D3

Olfactory receptor 12D3 (OR12D3) is a protein from Homo sapiens identified by UniProt accession Q9UGF7, 316 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.

Target properties

Protein name	Olfactory receptor 12D3
UniProt accession	Q9UGF7
Gene	OR12D3
Organism	Homo sapiens
Length	316 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (42)

Diseases linked to this target (Open Targets).

schizophrenia · score 0.21
clear cell renal carcinoma · score 0.18
ovarian cancer · score 0.18
hepatocellular carcinoma · score 0.18
breast adenocarcinoma · score 0.18
chronic obstructive pulmonary disease · score 0.11
neuroimaging measurement · score 0.11
major depressive disorder · score 0.10
unipolar depression · score 0.10
glomerular filtration rate · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UGF7-F1	alphafold	PREDICTED	81.86	—

Amino-acid sequence (316 residues)

MENVTTMNEF LLLGLTGVQE LQPFFFGIFL IIYLINLIGN GSILVMVVLE PQLHSPMYFF LGNLSCLDIS YSSVTLPKLL VNLVCSRRAI SFLGCITQLH FFHFLGSTEA ILLAIMAFDR FVAICNPLRY TVIMNPQVCI LLAAAAWLIS FFYALMHSVM TAHLSFCGSQ KLNHFFYDVK PLLELACSDT LLNQWLLSIV TGSISMGAFF LTLLSCFYVI GFLLFKNRSC RILHKALSTC ASHFMVVCLF YGPVGFTYIR PASATSMIQD RIMAIMYSAV TPVLNPLIYT LRNKEVMMAL KKIFGRKLFK DWQQHH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards