About Solute carrier family 23 member 2
Solute carrier family 23 member 2 (SLC23A2) is a protein
from Homo sapiens identified by UniProt accession
Q9UGH3, 650 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | Solute carrier family 23 member 2 |
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| UniProt accession | Q9UGH3 |
|---|
| Gene | SLC23A2 |
|---|
| Organism | Homo sapiens |
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| Length | 650 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (68)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- mean corpuscular volume · score 0.49
- Red cell distribution width · score 0.49
- mean corpuscular hemoglobin · score 0.45
- mean corpuscular hemoglobin concentration · score 0.41
- urate measurement · score 0.41
- bone density · score 0.41
- leukocyte count · score 0.32
- mean platelet volume · score 0.10
- open-angle glaucoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UGH3-F1 | alphafold | PREDICTED | 77.35 | — |
Amino-acid sequence (650 residues)
MMGIGKNTTS KSMEAGSSTE GKYEDEAKHP AFFTLPVVIN GGATSSGEQD NEDTELMAIY TTENGIAEKS SLAETLDSTG SLDPQRSDMI YTIEDVPPWY LCIFLGLQHY LTCFSGTIAV PFLLADAMCV GYDQWATSQL IGTIFFCVGI TTLLQTTFGC RLPLFQASAF AFLAPARAIL SLDKWKCNTT DVSVANGTAE LLHTEHIWYP RIREIQGAII MSSLIEVVIG LLGLPGALLK YIGPLTITPT VALIGLSGFQ AAGERAGKHW GIAMLTIFLV LLFSQYARNV KFPLPIYKSK KGWTAYKLQL FKMFPIILAI LVSWLLCFIF TVTDVFPPDS TKYGFYARTD ARQGVLLVAP WFKVPYPFQW GLPTVSAAGV IGMLSAVVAS IIESIGDYYA CARLSCAPPP PIHAINRGIF VEGLSCVLDG IFGTGNGSTS SSPNIGVLGI TKVGSRRVIQ CGAALMLALG MIGKFSALFA SLPDPVLGAL FCTLFGMITA VGLSNLQFID LNSSRNLFVL GFSIFFGLVL PSYLRQNPLV TGITGIDQVL NVLLTTAMFV GGCVAFILDN TIPGTPEERG IRKWKKGVGK GNKSLDGMES YNLPFGMNII KKYRCFSYLP ISPTFVGYTW KGLRKSDNSR SSDEDSQATG
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