About Testin
Testin (TES) is a protein
from Homo sapiens identified by UniProt accession
Q9UGI8, 421 residues long.
MolForge cross-references it against 0 known binders and
122 disease associations.
Target properties
| Protein name | Testin |
|---|
| UniProt accession | Q9UGI8 |
|---|
| Gene | TES |
|---|
| Organism | Homo sapiens |
|---|
| Length | 421 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (122)
Diseases linked to this target (Open Targets).
- intraocular pressure measurement · score 0.39
- cortical thickness · score 0.36
- glaucoma · score 0.33
- cortical surface area measurement · score 0.31
- brain measurement · score 0.29
- body mass index · score 0.17
- Hereditary breast and ovarian cancer syndrome · score 0.12
- hereditary breast ovarian cancer syndrome · score 0.12
- chronotype measurement · score 0.10
- platelet count · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UGI8-F1 | alphafold | PREDICTED | 85.44 | — |
Amino-acid sequence (421 residues)
MDLENKVKKM GLGHEQGFGA PCLKCKEKCE GFELHFWRKI CRNCKCGQEE HDVLLSNEED RKVGKLFEDT KYTTLIAKLK SDGIPMYKRN VMILTNPVAA KKNVSINTVT YEWAPPVQNQ ALARQYMQML PKEKQPVAGS EGAQYRKKQL AKQLPAHDQD PSKCHELSPR EVKEMEQFVK KYKSEALGVG DVKLPCEMDA QGPKQMNIPG GDRSTPAAVG AMEDKSAEHK RTQYSCYCCK LSMKEGDPAI YAERAGYDKL WHPACFVCST CHELLVDMIY FWKNEKLYCG RHYCDSEKPR CAGCDELIFS NEYTQAENQN WHLKHFCCFD CDSILAGEIY VMVNDKPVCK PCYVKNHAVV CQGCHNAIDP EVQRVTYNNF SWHASTECFL CSCCSKCLIG QKFMPVEGMV FCSVECKKRM S
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