Fetuin-B (FETUB)

About Fetuin-B

Fetuin-B (FETUB) is a protein from Homo sapiens identified by UniProt accession Q9UGM5, 382 residues long. MolForge cross-references it against 0 known binders and 140 disease associations.

Target properties

Protein name	Fetuin-B
UniProt accession	Q9UGM5
Gene	FETUB
Organism	Homo sapiens
Length	382 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (140)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.30
persulfide dioxygenase ETHE1, mitochondrial measurement · score 0.28
fetuin-B measurement · score 0.27
electrocardiography · score 0.12
insulin resistance · score 0.10
polycystic ovary syndrome · score 0.09
Insulin resistance · score 0.09
Female infertility due to fertilization defect · score 0.09
coagulation factor measurement · score 0.08
metabolic syndrome · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UGM5-F1	alphafold	PREDICTED	81.07	—

Amino-acid sequence (382 residues)

MGLLLPLALC ILVLCCGAMS PPQLALNPSA LLSRGCNDSD VLAVAGFALR DINKDRKDGY VLRLNRVNDA QEYRRGGLGS LFYLTLDVLE TDCHVLRKKA WQDCGMRIFF ESVYGQCKAI FYMNNPSRVL YLAAYNCTLR PVSKKKIYMT CPDCPSSIPT DSSNHQVLEA ATESLAKYNN ENTSKQYSLF KVTRASSQWV VGPSYFVEYL IKESPCTKSQ ASSCSLQSSD SVPVGLCKGS LTRTHWEKFV SVTCDFFESQ APATGSENSA VNQKPTNLPK VEESQQKNTP PTDSPSKAGP RGSVQYLPDL DDKNSQEKGP QEAFPVHLDL TTNPQGETLD ISFLFLEPME EKLVVLPFPK EKARTAECPG PAQNASPLVL PP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards