About CMRF35-like molecule 8
CMRF35-like molecule 8 (CD300A) is a protein
from Homo sapiens identified by UniProt accession
Q9UGN4, 299 residues long.
MolForge cross-references it against 0 known binders and
91 disease associations.
Target properties
| Protein name | CMRF35-like molecule 8 |
|---|
| UniProt accession | Q9UGN4 |
|---|
| Gene | CD300A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 299 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (91)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.41
- myeloid white cell count · score 0.15
- inflammatory bowel disease · score 0.12
- acute myeloid leukemia · score 0.10
- neoplasm · score 0.09
- diffuse large B-cell lymphoma · score 0.08
- non-small cell lung carcinoma · score 0.07
- alkaline phosphatase measurement · score 0.07
- melanoma · score 0.07
- infection · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UGN4-F1 | alphafold | PREDICTED | 70.69 | — |
Amino-acid sequence (299 residues)
MWLPWALLLL WVPGCFALSK CRTVAGPVGG SLSVQCPYEK EHRTLNKYWC RPPQIFLCDK IVETKGSAGK RNGRVSIRDS PANLSFTVTL ENLTEEDAGT YWCGVDTPWL RDFHDPVVEV EVSVFPASTS MTPASITAAK TSTITTAFPP VSSTTLFAVG ATHSASIQEE TEEVVNSQLP LLLSLLALLL LLLVGASLLA WRMFQKWIKA GDHSELSQNP KQAATQSELH YANLELLMWP LQEKPAPPRE VEVEYSTVAS PREELHYASV VFDSNTNRIA AQRPREEEPD SDYSVIRKT
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