About LIM domain-containing protein 1
LIM domain-containing protein 1 (LIMD1) is a protein
from Homo sapiens identified by UniProt accession
Q9UGP4, 676 residues long.
MolForge cross-references it against 0 known binders and
122 disease associations.
Target properties
| Protein name | LIM domain-containing protein 1 |
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| UniProt accession | Q9UGP4 |
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| Gene | LIMD1 |
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| Organism | Homo sapiens |
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| Length | 676 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (122)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.28
- body height · score 0.26
- clear cell renal carcinoma · score 0.25
- IGF-1 measurement · score 0.25
- breast adenocarcinoma · score 0.18
- viral load · score 0.14
- non-small cell lung carcinoma · score 0.10
- lung adenocarcinoma · score 0.09
- neoplasm · score 0.08
- cancer · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UGP4-F1 | alphafold | PREDICTED | 56.69 | — |
Amino-acid sequence (676 residues)
MDKYDDLGLE ASKFIEDLNM YEASKDGLFR VDKGAGNNPE FEETRRVFAT KMAKIHLQQQ QQQLLQEETL PRGSRGPVNG GGRLGPQARW EVVGSKLTVD GAAKPPLAAS TGAPGAVTTL AAGQPPYPPQ EQRSRPYLHG TRHGSQDCGS RESLATSEMS AFHQPGPCED PSCLTHGDYY DNLSLASPKW GDKPGVSPSI GLSVGSGWPS SPGSDPPLPK PCGDHPLNHR QLSLSSSRSS EGSLGGQNSG IGGRSSEKPT GLWSTASSQR VSPGLPSPNL ENGAPAVGPV QPRTPSVSAP LALSCPRQGG LPRSNSGLGG EVSGVMSKPN VDPQPWFQDG PKSYLSSSAP SSSPAGLDGS QQGAVPGLGP KPGCTDLGTG PKLSPTSLVH PVMSTLPELS CKEGPLGWSS DGSLGSVLLD SPSSPRVRLP CQPLVPGPEL RPSAAELKLE ALTQRLEREM DAHPKADYFG ACVKCSKGVF GAGQACQAMG NLYHDTCFTC AACSRKLRGK AFYFVNGKVF CEEDFLYSGF QQSADRCFLC GHLIMDMILQ ALGKSYHPGC FRCVICNECL DGVPFTVDSE NKIYCVRDYH KVLAPKCAAC GLPILPPEGS DETIRVVSMD RDYHVECYHC EDCGLELNDE DGHRCYPLED HLFCHSCHVK RLEKRPSSTA LHQHHF
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