About Calcium channel flower homolog
Calcium channel flower homolog (CACFD1) is a protein
from Homo sapiens identified by UniProt accession
Q9UGQ2, 172 residues long.
MolForge cross-references it against 0 known binders and
53 disease associations.
Target properties
| Protein name | Calcium channel flower homolog |
|---|
| UniProt accession | Q9UGQ2 |
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| Gene | CACFD1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 172 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (53)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.33
- alkaline phosphatase measurement · score 0.26
- platelet endothelial cell adhesion molecule measurement · score 0.26
- forced expiratory volume · score 0.23
- thyroid gland adenocarcinoma · score 0.23
- liver enzyme measurement · score 0.23
- peak expiratory flow · score 0.23
- vital capacity · score 0.22
- e-selectin measurement · score 0.22
- aspartate aminotransferase measurement · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UGQ2-F1 | alphafold | PREDICTED | 61.88 | — |
Amino-acid sequence (172 residues)
MSSSGGAPGA SASSAPPAQE EGMTWWYRWL CRLSGVLGAV SCAISGLFNC ITIHPLNIAA GVWMIMNAFI LLLCEAPFCC QFIEFANTVA EKVDRLRSWQ KAVFYCGMAV VPIVISLTLT TLLGNAIAFA TGVLYGLSAL GKKGDAISYA RIQQQRQQAD EEKLAETLEG EL
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