About Solute carrier family 2, facilitated glucose transporter member 6
Solute carrier family 2, facilitated glucose transporter member 6 (SLC2A6) is a protein
from Homo sapiens identified by UniProt accession
Q9UGQ3, 507 residues long.
MolForge cross-references it against 0 known binders and
48 disease associations.
Target properties
| Protein name | Solute carrier family 2, facilitated glucose transporter member 6 |
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| UniProt accession | Q9UGQ3 |
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| Gene | SLC2A6 |
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| Organism | Homo sapiens |
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| Length | 507 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (48)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.42
- basophil count · score 0.19
- platelet endothelial cell adhesion molecule measurement · score 0.13
- a disintegrin and metalloproteinase with thrombospondin motifs 13 measurement · score 0.08
- lung adenocarcinoma · score 0.07
- body height · score 0.06
- blood protein measurement · score 0.05
- forced expiratory volume · score 0.05
- peak expiratory flow · score 0.05
- ADAMTS13 measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UGQ3-F1 | alphafold | PREDICTED | 81.64 | — |
Amino-acid sequence (507 residues)
MQEPLLGAEG PDYDTFPEKP PPSPGDRARV GTLQNKRVFL ATFAAVLGNF SFGYALVYTS PVIPALERSL DPDLHLTKSQ ASWFGSVFTL GAAAGGLSAM ILNDLLGRKL SIMFSAVPSA AGYALMAGAH GLWMLLLGRT LTGFAGGLTA ACIPVYVSEI APPGVRGALG ATPQLMAVFG SLSLYALGLL LPWRWLAVAG EAPVLIMILL LSFMPNSPRF LLSRGRDEEA LRALAWLRGT DVDVHWEFEQ IQDNVRRQSS RVSWAEARAP HVCRPITVAL LMRLLQQLTG ITPILVYLQS IFDSTAVLLP PKDDAAIVGA VRLLSVLIAA LTMDLAGRKV LLFVSAAIMF AANLTLGLYI HFGPRPLSPN STAGLESESW GDLAQPLAAP AGYLTLVPLL ATMLFIMGYA VGWGPITWLL MSEVLPLRAR GVASGLCVLA SWLTAFVLTK SFLPVVSTFG LQVPFFFFAA ICLVSLVFTG CCVPETKGRS LEQIESFFRT GRRSFLR
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