About Zinc finger CCCH domain-containing protein 7B
Zinc finger CCCH domain-containing protein 7B (ZC3H7B) is a protein
from Homo sapiens identified by UniProt accession
Q9UGR2, 977 residues long.
MolForge cross-references it against 0 known binders and
123 disease associations.
Target properties
| Protein name | Zinc finger CCCH domain-containing protein 7B |
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| UniProt accession | Q9UGR2 |
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| Gene | ZC3H7B |
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| Organism | Homo sapiens |
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| Length | 977 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (123)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.17
- eosinophil count · score 0.14
- neuroticism measurement · score 0.13
- eosinophil percentage of leukocytes · score 0.12
- mathematical ability · score 0.12
- feeling tense measurement · score 0.10
- neurotic disorder · score 0.10
- platelet count · score 0.10
- neutrophil percentage of granulocytes · score 0.10
- diet measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UGR2-F1 | alphafold | PREDICTED | 68.57 | — |
Amino-acid sequence (977 residues)
MERQKRKADI EKGLQFIQST LPLKQEEYEA FLLKLVQNLF AEGNDLFREK DYKQALVQYM EGLNVADYAA SDQVALPREL LCKLHVNRAA CYFTMGLYEK ALEDSEKALG LDSESIRALF RKARALNELG RHKEAYECSS RCSLALPHDE SVTQLGQELA QKLGLRVRKA YKRPQELETF SLLSNGTAAG VADQGTSNGL GSIDDIETDC YVDPRGSPAL LPSTPTMPLF PHVLDLLAPL DSSRTLPSTD SLDDFSDGDV FGPELDTLLD SLSLVQGGLS GSGVPSELPQ LIPVFPGGTP LLPPVVGGSI PVSSPLPPAS FGLVMDPSKK LAASVLDALD PPGPTLDPLD LLPYSETRLD ALDSFGSTRG SLDKPDSFME ETNSQDHRPP SGAQKPAPSP EPCMPNTALL IKNPLAATHE FKQACQLCYP KTGPRAGDYT YREGLEHKCK RDILLGRLRS SEDQTWKRIR PRPTKTSFVG SYYLCKDMIN KQDCKYGDNC TFAYHQEEID VWTEERKGTL NRDLLFDPLG GVKRGSLTIA KLLKEHQGIF TFLCEICFDS KPRIISKGTK DSPSVCSNLA AKHSFYNNKC LVHIVRSTSL KYSKIRQFQE HFQFDVCRHE VRYGCLREDS CHFAHSFIEL KVWLLQQYSG MTHEDIVQES KKYWQQMEAH AGKASSSMGA PRTHGPSTFD LQMKFVCGQC WRNGQVVEPD KDLKYCSAKA RHCWTKERRV LLVMSKAKRK WVSVRPLPSI RNFPQQYDLC IHAQNGRKCQ YVGNCSFAHS PEERDMWTFM KENKILDMQQ TYDMWLKKHN PGKPGEGTPI SSREGEKQIQ MPTDYADIMM GYHCWLCGKN SNSKKQWQQH IQSEKHKEKV FTSDSDASGW AFRFPMGEFR LCDRLQKGKA CPDGDKCRCA HGQEELNEWL DRREVLKQKL AKARKDMLLC PRDDDFGKYN FLLQEDGDLA GATPEAPAAA ATATTGE
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