Ragulator complex protein LAMTOR3 (LAMTOR3)

About Ragulator complex protein LAMTOR3

Ragulator complex protein LAMTOR3 (LAMTOR3) is a protein from Homo sapiens identified by UniProt accession Q9UHA4, 124 residues long. MolForge cross-references it against 0 known binders and 145 disease associations.

Target properties

Protein name	Ragulator complex protein LAMTOR3
UniProt accession	Q9UHA4
Gene	LAMTOR3
Organism	Homo sapiens
Length	124 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (145)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.50
neuroinflammatory disorder · score 0.46
Alzheimer disease · score 0.45
Parkinson disease · score 0.45
multiple sclerosis · score 0.45
lysosomal storage disease · score 0.45
glioblastoma multiforme · score 0.30
mean corpuscular volume · score 0.27
mean corpuscular hemoglobin concentration · score 0.20
head and neck squamous cell carcinoma · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UHA4-F1	alphafold	PREDICTED	95.51	—

Amino-acid sequence (124 residues)

MADDLKRFLY KKLPSVEGLH AIVVSDRDGV PVIKVANDNA PEHALRPGFL STFALATDQG SKLGLSKNKS IICYYNTYQV VQFNRLPLVV SFIASSSANT GLIVSLEKEL APLFEELRQV VEVS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards