About Interleukin-19
Interleukin-19 (IL19) is a protein
from Homo sapiens identified by UniProt accession
Q9UHD0, 177 residues long.
MolForge cross-references it against 0 known binders and
232 disease associations.
Target properties
| Protein name | Interleukin-19 |
|---|
| UniProt accession | Q9UHD0 |
|---|
| Gene | IL19 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 177 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (232)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.33
- ulcerative colitis · score 0.29
- inflammatory bowel disease · score 0.29
- type 1 diabetes mellitus · score 0.27
- Behcet's syndrome · score 0.25
- Crohn's disease · score 0.24
- eosinophil percentage of leukocytes · score 0.24
- systemic lupus erythematosus · score 0.22
- HIV-1 infection · score 0.22
- mosquito bite reaction itch intensity measurement · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UHD0-F1 | alphafold | PREDICTED | 87.59 | — |
Amino-acid sequence (177 residues)
MKLQCVSLWL LGTILILCSV DNHGLRRCLI STDMHHIEES FQEIKRAIQA KDTFPNVTIL STLETLQIIK PLDVCCVTKN LLAFYVDRVF KDHQEPNPKI LRKISSIANS FLYMQKTLRQ CQEQRQCHCR QEATNATRVI HDNYDQLEVH AAAIKSLGEL DVFLAWINKN HEVMFSA
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