About Prenylated Rab acceptor protein 1
Prenylated Rab acceptor protein 1 (RABAC1) is a protein
from Homo sapiens identified by UniProt accession
Q9UI14, 185 residues long.
MolForge cross-references it against 0 known binders and
56 disease associations.
Target properties
| Protein name | Prenylated Rab acceptor protein 1 |
|---|
| UniProt accession | Q9UI14 |
|---|
| Gene | RABAC1 |
|---|
| Organism | Homo sapiens |
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| Length | 185 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (56)
Diseases linked to this target (Open Targets).
- early-onset non-syndromic cataract · score 0.06
- isolated ectopia lentis · score 0.06
- Cataract-microcornea syndrome · score 0.06
- Total congenital cataract · score 0.05
- Cataract with Y-shaped suture opacities · score 0.05
- brain measurement · score 0.05
- neuroimaging measurement · score 0.05
- cataract · score 0.05
- Familial ocular anterior segment mesenchymal dysgenesis · score 0.05
- hereditary hyperferritinemia with congenital cataracts · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UI14-F1 | alphafold | PREDICTED | 83.02 | — |
Amino-acid sequence (185 residues)
MAAQKDQQKD AEAEGLSGTT LLPKLIPSGA GREWLERRRA TIRPWSTFVD QQRFSRPRNL GELCQRLVRN VEYYQSNYVF VFLGLILYCV VTSPMLLVAL AVFFGACYIL YLRTLESKLV LFGREVSPAH QYALAGGISF PFFWLAGAGS AVFWVLGATL VVIGSHAAFH QIEAVDGEEL QMEPV
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