About Transgelin-3
Transgelin-3 (TAGLN3) is a protein
from Homo sapiens identified by UniProt accession
Q9UI15, 199 residues long.
MolForge cross-references it against 0 known binders and
35 disease associations.
Target properties
| Protein name | Transgelin-3 |
|---|
| UniProt accession | Q9UI15 |
|---|
| Gene | TAGLN3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 199 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (35)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- drug use measurement · score 0.18
- atrial fibrillation · score 0.06
- lung carcinoma · score 0.04
- glucuronate measurement · score 0.03
- PR interval · score 0.03
- lobe attachment · score 0.03
- glioblastoma multiforme · score 0.03
- Down syndrome · score 0.03
- diastolic blood pressure · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UI15-F1 | alphafold | PREDICTED | 87.52 | — |
Amino-acid sequence (199 residues)
MANRGPSYGL SREVQEKIEQ KYDADLENKL VDWIILQCAE DIEHPPPGRA HFQKWLMDGT VLCKLINSLY PPGQEPIPKI SESKMAFKQM EQISQFLKAA ETYGVRTTDI FQTVDLWEGK DMAAVQRTLM ALGSVAVTKD DGCYRGEPSW FHRKAQQNRR GFSEEQLRQG QNVIGLQMGS NKGASQAGMT GYGMPRQIM
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