Zinc finger protein 639 (ZNF639)

About Zinc finger protein 639

Zinc finger protein 639 (ZNF639) is a protein from Homo sapiens identified by UniProt accession Q9UID6, 485 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Zinc finger protein 639
UniProt accession	Q9UID6
Gene	ZNF639
Organism	Homo sapiens
Length	485 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.28
platelet crit · score 0.09
atrial fibrillation · score 0.04
oral squamous cell carcinoma · score 0.03
neoplasm · score 0.02
infection · score 0.02
infect · score 0.02
HIV-1 infection · score 0.01
esophageal squamous cell carcinoma · score 0.01
viral disease · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UID6-F1	alphafold	PREDICTED	52.86	—

Amino-acid sequence (485 residues)

MNEYPKKRKR KTLHPSRYSD SSGISRIADG FNGIFSDHCY SVCSMRQPDL KYFDNKDDDS DTETSNDLPK FADGIKARNR NQNYLVPSPV LRILDHTAFS TEKSADIVIC DEECDSPESV NQQTQEESPI EVHTAEDVPI AVEVHAISED YDIETENNSS ESLQDQTDEE PPAKLCKILD KSQALNVTAQ QKWPLLRANS SGLYKCELCE FNSKYFSDLK QHMILKHKRT DSNVCRVCKE SFSTNMLLIE HAKLHEEDPY ICKYCDYKTV IFENLSQHIA DTHFSDHLYW CEQCDVQFSS SSELYLHFQE HSCDEQYLCQ FCEHETNDPE DLHSHVVNEH ACKLIELSDK YNNGEHGQYS LLSKITFDKC KNFFVCQVCG FRSRLHTNVN RHVAIEHTKI FPHVCDDCGK GFSSMLEYCK HLNSHLSEGI YLCQYCEYST GQIEDLKIHL DFKHSADLPH KCSDCLMRFG NERELISHLP VHETT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards