About Dual specificity protein phosphatase 13B
Dual specificity protein phosphatase 13B (DUSP13B) is a protein
from Homo sapiens identified by UniProt accession
Q9UII6, 198 residues long.
MolForge cross-references it against 0 known binders and
26 disease associations.
Target properties
| Protein name | Dual specificity protein phosphatase 13B |
|---|
| UniProt accession | Q9UII6 |
|---|
| Gene | DUSP13B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 198 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (26)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.33
- body fat percentage · score 0.28
- fat body mass · score 0.26
- self reported educational attainment · score 0.26
- lean body mass · score 0.23
- unipolar depression · score 0.22
- body mass index · score 0.22
- insomnia measurement · score 0.20
- high density lipoprotein cholesterol measurement · score 0.20
- smoking initiation · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UII6-F1 | alphafold | PREDICTED | 90.72 | — |
Amino-acid sequence (198 residues)
MDSLQKQDLR RPKIHGAVQA SPYQPPTLAS LQRLLWVRQA ATLNHIDEVW PSLFLGDAYA ARDKSKLIQL GITHVVNAAA GKFQVDTGAK FYRGMSLEYY GIEADDNPFF DLSVYFLPVA RYIRAALSVP QGRVLVHCAM GVSRSATLVL AFLMICENMT LVEAIQTVQA HRNICPNSGF LRQLQVLDNR LGRETGRF
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