About Palmitoyltransferase ZDHHC2
Palmitoyltransferase ZDHHC2 (ZDHHC2) is a protein
from Homo sapiens identified by UniProt accession
Q9UIJ5, 367 residues long.
MolForge cross-references it against 0 known binders and
126 disease associations.
Target properties
| Protein name | Palmitoyltransferase ZDHHC2 |
|---|
| UniProt accession | Q9UIJ5 |
|---|
| Gene | ZDHHC2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 367 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (126)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.44
- self reported educational attainment · score 0.41
- COVID-19 · score 0.37
- PHF-tau measurement · score 0.31
- cutaneous melanoma · score 0.17
- pancreatic adenocarcinoma · score 0.16
- visual perception measurement · score 0.14
- neoplasm · score 0.09
- radiculopathy · score 0.09
- hepatocellular carcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UIJ5-F1 | alphafold | PREDICTED | 81.92 | — |
Amino-acid sequence (367 residues)
MAPSGPGSSA RRRCRRVLYW IPVVFITLLL GWSYYAYAIQ LCIVSMENTG EQVVCLMAYH LLFAMFVWSY WKTIFTLPMN PSKEFHLSYA EKDLLEREPR GEAHQEVLRR AAKDLPIYTR TMSGAIRYCD RCQLIKPDRC HHCSVCDKCI LKMDHHCPWV NNCVGFSNYK FFLLFLAYSL LYCLFIAATD LQYFIKFWTN GLPDTQAKFH IMFLFFAAAM FSVSLSSLFG YHCWLVSKNK STLEAFRSPV FRHGTDKNGF SLGFSKNMRQ VFGDEKKYWL LPIFSSLGDG CSFPTCLVNQ DPEQASTPAG LNSTAKNLEN HQFPAKPLRE SQSHLLTDSQ SWTESSINPG KCKAGMSNPA LTMENET
Explore Palmitoyltransferase ZDHHC2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets