About Short coiled-coil protein
Short coiled-coil protein (SCOC) is a protein
from Homo sapiens identified by UniProt accession
Q9UIL1, 159 residues long.
MolForge cross-references it against 0 known binders and
123 disease associations.
Target properties
| Protein name | Short coiled-coil protein |
|---|
| UniProt accession | Q9UIL1 |
|---|
| Gene | SCOC |
|---|
| Organism | Homo sapiens |
|---|
| Length | 159 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (123)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- sodium measurement · score 0.35
- mean arterial pressure · score 0.26
- systolic blood pressure · score 0.26
- diastolic blood pressure · score 0.26
- familial atrial fibrillation · score 0.07
- Familial short QT syndrome · score 0.07
- Romano-Ward syndrome · score 0.07
- Brugada syndrome · score 0.07
- Arrhythmogenic right ventricular dysplasia · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UIL1-F1 | alphafold | PREDICTED | 66.06 | — |
Amino-acid sequence (159 residues)
MRRRVFSSQD WRASGWDGMG FFSRRTFCGR SGRSCRGQLV QVSRPEVSAG SLLLPAPQAE DHSSRILYPR PKSLLPKMMN ADMDAVDAEN QVELEEKTRL INQVLELQHT LEDLSARVDA VKEENLKLKS ENQVLGQYIE NLMSASSVFQ TTDTKSKRK
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