About PHD finger protein 11
PHD finger protein 11 (PHF11) is a protein
from Homo sapiens identified by UniProt accession
Q9UIL8, 331 residues long.
MolForge cross-references it against 0 known binders and
74 disease associations.
Target properties
| Protein name | PHD finger protein 11 |
|---|
| UniProt accession | Q9UIL8 |
|---|
| Gene | PHF11 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 331 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (74)
Diseases linked to this target (Open Targets).
- platelet count · score 0.35
- eosinophil count · score 0.24
- protein measurement · score 0.24
- mean corpuscular volume · score 0.15
- cystatin C measurement · score 0.13
- myeloid white cell count · score 0.10
- leukocyte count · score 0.10
- attention deficit hyperactivity disorder · score 0.09
- monocyte count · score 0.07
- schizophrenia 15 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UIL8-F1 | alphafold | PREDICTED | 73.71 | — |
Amino-acid sequence (331 residues)
MAQASPPRPE RVLGASSPEA RPAQEALLLP TGVFQVAEKM EKRTCALCPK DVEYNVLYFA QSENIAAHEN CLLYSSGLVE CEDQDPLNPD RSFDVESVKK EIQRGRKLKC KFCHKRGATV GCDLKNCNKN YHFFCAKKDD AVPQSDGVRG IYKLLCQQHA QFPIIAQSAK FSGVKRKRGR KKPLSGNHVQ PPETMKCNTF IRQVKEEHGR HTDATVKVPF LKKCKEAGLL NYLLEEILDK VHSIPEKLMD ETTSESDYEE IGSALFDCRL FEDTFVNFQA AIEKKIHASQ QRWQQLKEEI ELLQDLKQTL CSFQENRDLM SSSTSISSLS Y
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