Serpin B13 (SERPINB13)

About Serpin B13

Serpin B13 (SERPINB13) is a protein from Homo sapiens identified by UniProt accession Q9UIV8, 391 residues long. MolForge cross-references it against 0 known binders and 78 disease associations.

Target properties

Protein name	Serpin B13
UniProt accession	Q9UIV8
Gene	SERPINB13
Organism	Homo sapiens
Length	391 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (78)

Diseases linked to this target (Open Targets).

eosinophil count · score 0.35
eosinophil percentage of leukocytes · score 0.25
neutrophil percentage of granulocytes · score 0.18
sum of eosinophil and basophil counts · score 0.16
prostate carcinoma · score 0.11
prostate cancer · score 0.11
Familial prostate cancer · score 0.11
eosinophil percentage of granulocytes · score 0.08
non-small cell lung carcinoma · score 0.06
vitamin D measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UIV8-F1	alphafold	PREDICTED	86.79	—

Amino-acid sequence (391 residues)

MDSLGAVSTR LGFDLFKELK KTNDGNIFFS PVGILTAIGM VLLGTRGATA SQLEEVFHSE KETKSSRIKA EEKEVIENTE AVHQQFQKFL TEISKLTNDY ELNITNRLFG EKTYLFLQKY LDYVEKYYHA SLEPVDFVNA ADESRKKINS WVESKTNEKI KDLFPDGSIS SSTKLVLVNM VYFKGQWDRE FKKENTKEEK FWMNKSTSKS VQMMTQSHSF SFTFLEDLQA KILGIPYKNN DLSMFVLLPN DIDGLEKIID KISPEKLVEW TSPGHMEERK VNLHLPRFEV EDGYDLEAVL AAMGMGDAFS EHKADYSGMS SGSGLYAQKF LHSSFVAVTE EGTEAAAATG IGFTVTSAPG HENVHCNHPF LFFIRHNESN SILFFGRFSS P

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards