About RWD domain-containing protein 2A
RWD domain-containing protein 2A (RWDD2A) is a protein
from Homo sapiens identified by UniProt accession
Q9UIY3, 292 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | RWD domain-containing protein 2A |
|---|
| UniProt accession | Q9UIY3 |
|---|
| Gene | RWDD2A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 292 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.28
- brain measurement · score 0.08
- bipolar disorder · score 0.07
- body mass index · score 0.07
- lean body mass · score 0.06
- waist circumference · score 0.05
- vitamin D measurement · score 0.04
- fat body mass · score 0.04
- base metabolic rate measurement · score 0.04
- whole body water mass · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UIY3-F1 | alphafold | PREDICTED | 85.44 | — |
Amino-acid sequence (292 residues)
MSASVKESLQ LQLLEMEMLF SMFPNQGEVK LEDVNALTNI KRYLEGTREA LPPKIEFVIT LQIEEPKVKI DLQVTMPHSY PYVALQLFGR SSELDRHQQL LLNKGLTSYI GTFDPGELCV CAAIQWLQDN SASYFLNRKL VYEPSTQAKP VKNTFLRMWI YSHHIYQQDL RKKILDVGKR LDVTGFCMTG KPGIICVEGF KEHCEEFWHT IRYPNWKHIS CKHAESVETE GNGEDLRLFH SFEELLLEAH GDYGLRNDYH MNLGQFLEFL KKHKSEHVFQ ILFGIESKSS DS
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