About Uncharacterized protein C3orf18
Uncharacterized protein C3orf18 (C3orf18) is a protein
from Homo sapiens identified by UniProt accession
Q9UK00, 162 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | Uncharacterized protein C3orf18 |
| UniProt accession | Q9UK00 |
| Gene | C3orf18 |
| Organism | Homo sapiens |
| Length | 162 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- body mass index · score 0.27
- diastolic blood pressure · score 0.27
- systolic blood pressure · score 0.26
- serum gamma-glutamyl transferase measurement · score 0.22
- vital capacity · score 0.15
- chronotype measurement · score 0.08
- platelet count · score 0.07
- eosinophil count · score 0.07
- BMI-adjusted waist circumference · score 0.06
- coffee consumption measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9UK00-F1 | alphafold | PREDICTED | 63.62 | — |
Amino-acid sequence (162 residues)
MNSRTASARG WFSSRPPTSE SDLEPATDGP ASETTTLSPE ATTFNDTRIP DAAGGTAGVG TMLLSFGIIT VIGLAVALVL YIRKKKRLEK LRHQLMPMYN FDPTEEQDEL EQELLEHGRD AASVQAATSV QAMQGKTTLP SQGPLQRPSR LVFTDVANAI HA
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