Nocturnin (NOCT)

About Nocturnin

Nocturnin (NOCT) is a protein from Homo sapiens identified by UniProt accession Q9UK39, 431 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.

Target properties

Protein name	Nocturnin
UniProt accession	Q9UK39
Gene	NOCT
Organism	Homo sapiens
Length	431 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (61)

Diseases linked to this target (Open Targets).

antisocial behaviour measurement · score 0.30
attention deficit hyperactivity disorder · score 0.30
substance abuse · score 0.30
smoking status measurement · score 0.25
body height · score 0.24
body mass index · score 0.18
self reported educational attainment · score 0.15
body weight · score 0.15
neuroticism measurement · score 0.13
creatinine measurement · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UK39-F1	alphafold	PREDICTED	82.62	—

Amino-acid sequence (431 residues)

MFHSPRRLCS ALLQRDAPGL RRLPAPGLRR PLSPPAAVPR PASPRLLAAA SAASGAARSC SRTVCSMGTG TSRLYSALAK TLNSSAASQH PEYLVSPDPE HLEPIDPKEL LEECRAVLHT RPPRFQRDFV DLRTDCPSTH PPIRVMQWNI LAQALGEGKD NFVQCPVEAL KWEERKCLIL EEILAYQPDI LCLQEVDHYF DTFQPLLSRL GYQGTFFPKP WSPCLDVEHN NGPDGCALFF LQNRFKLVNS ANIRLTAMTL KTNQVAIAQT LECKESGRQF CIAVTHLKAR TGWERFRSAQ GCDLLQNLQN ITQGAKIPLI VCGDFNAEPT EEVYKHFASS SLNLNSAYKL LSADGQSEPP YTTWKIRTSG ECRHTLDYIW YSKHALNVRS ALDLLTEEQI GPNRLPSFNY PSDHLSLVCD FSFTEESDGL S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards