About Jupiter microtubule associated homolog 1
Jupiter microtubule associated homolog 1 (JPT1) is a protein
from Homo sapiens identified by UniProt accession
Q9UK76, 154 residues long.
MolForge cross-references it against 0 known binders and
65 disease associations.
Target properties
| Protein name | Jupiter microtubule associated homolog 1 |
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| UniProt accession | Q9UK76 |
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| Gene | JPT1 |
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| Organism | Homo sapiens |
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| Length | 154 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (65)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.17
- serum gamma-glutamyl transferase measurement · score 0.16
- brain measurement · score 0.09
- attention deficit hyperactivity disorder · score 0.09
- cancer · score 0.08
- creatinine measurement · score 0.07
- schizophrenia 15 · score 0.07
- attention deficit-hyperactivity disorder 8 · score 0.07
- C-reactive protein measurement · score 0.07
- Tourette syndrome · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UK76-F1 | alphafold | PREDICTED | 63.16 | — |
Amino-acid sequence (154 residues)
MTTTTTFKGV DPNSRNSSRV LRPPGGGSNF SLGFDEPTEQ PVRKNKMASN IFGTPEENQA SWAKSAGAKS SGGREDLESS GLQRRNSSEA SSGDFLDLKG EGDIHENVDT DLPGSLGQSE EKPVPAAPVP SPVAPAPVPS RRNPPGGKSS LVLG
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