About mRNA turnover protein 4 homolog
mRNA turnover protein 4 homolog (MRTO4) is a protein
from Homo sapiens identified by UniProt accession
Q9UKD2, 239 residues long.
MolForge cross-references it against 0 known binders and
15 disease associations.
Target properties
| Protein name | mRNA turnover protein 4 homolog |
|---|
| UniProt accession | Q9UKD2 |
|---|
| Gene | MRTO4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 239 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (15)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.19
- blood protein measurement · score 0.09
- hepatocellular carcinoma · score 0.08
- urinary metabolite measurement · score 0.04
- neoplasm · score 0.03
- cancer · score 0.01
- infect · score 0.01
- infection · score 0.01
- lung adenocarcinoma · score 0.01
- COVID-19 · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UKD2-F1 | alphafold | PREDICTED | 89.36 | — |
Amino-acid sequence (239 residues)
MPKSKRDKKV SLTKTAKKGL ELKQNLIEEL RKCVDTYKYL FIFSVANMRN SKLKDIRNAW KHSRMFFGKN KVMMVALGRS PSDEYKDNLH QVSKRLRGEV GLLFTNRTKE EVNEWFTKYT EMDYARAGNK AAFTVSLDPG PLEQFPHSME PQLRQLGLPT ALKRGVVTLL SDYEVCKEGD VLTPEQARVL KLFGYEMAEF KVTIKYMWDS QSGRFQQMGD DLPESASEST EESDSEDDD
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