Phospholipase A and acyltransferase 4 (PLAAT4)

About Phospholipase A and acyltransferase 4

Phospholipase A and acyltransferase 4 (PLAAT4) is a protein from Homo sapiens identified by UniProt accession Q9UL19, 164 residues long. MolForge cross-references it against 0 known binders and 116 disease associations.

Target properties

Protein name	Phospholipase A and acyltransferase 4
UniProt accession	Q9UL19
Gene	PLAAT4
Organism	Homo sapiens
Length	164 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (116)

Diseases linked to this target (Open Targets).

neoplasm · score 0.10
infection · score 0.08
infect · score 0.08
breast cancer · score 0.07
pancreatic neoplasm · score 0.07
urinary bladder carcinoma · score 0.06
pancreatic adenocarcinoma · score 0.05
cancer · score 0.04
cholangiocarcinoma · score 0.04
urate measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UL19-F1	alphafold	PREDICTED	75.71	—

Amino-acid sequence (164 residues)

MASPHQEPKP GDLIEIFRLG YEHWALYIGD GYVIHLAPPS EYPGAGSSSV FSVLSNSAEV KRERLEDVVG GCCYRVNNSL DHEYQPRPVE VIISSAKEMV GQKMKYSIVS RNCEHFVTQL RYGKSRCKQV EKAKVEVGVA TALGILVVAG CSFAIRRYQK KATA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards