Ras-related protein Rab-22A (RAB22A)

About Ras-related protein Rab-22A

Ras-related protein Rab-22A (RAB22A) is a protein from Homo sapiens identified by UniProt accession Q9UL26, 194 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.

Target properties

Protein name	Ras-related protein Rab-22A
UniProt accession	Q9UL26
Gene	RAB22A
Organism	Homo sapiens
Length	194 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (64)

Diseases linked to this target (Open Targets).

appendicular lean mass · score 0.30
pancreatic adenocarcinoma · score 0.21
melanoma · score 0.08
breast cancer · score 0.08
hepatocellular carcinoma · score 0.08
Miyoshi myopathy · score 0.07
metabolite measurement · score 0.06
non-small cell lung carcinoma · score 0.06
neoplasm · score 0.05
cancer · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UL26-F1	alphafold	PREDICTED	89.46	—

Amino-acid sequence (194 residues)

MALRELKVCL LGDTGVGKSS IVWRFVEDSF DPNINPTIGA SFMTKTVQYQ NELHKFLIWD TAGQERFRAL APMYYRGSAA AIIVYDITKE ETFSTLKNWV KELRQHGPPN IVVAIAGNKC DLIDVREVME RDAKDYADSI HAIFVETSAK NAININELFI EISRRIPSTD ANLPSGGKGF KLRRQPSEPK RSCC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards