About Trafficking protein particle complex subunit 2-like protein
Trafficking protein particle complex subunit 2-like protein (TRAPPC2L) is a protein
from Homo sapiens identified by UniProt accession
Q9UL33, 140 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | Trafficking protein particle complex subunit 2-like protein |
|---|
| UniProt accession | Q9UL33 |
|---|
| Gene | TRAPPC2L |
|---|
| Organism | Homo sapiens |
|---|
| Length | 140 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (42)
Diseases linked to this target (Open Targets).
- encephalopathy, progressive, early-onset, with episodic rhabdomyolysis · score 0.56
- mucopolysaccharidosis type 4A · score 0.56
- neurodegenerative disease · score 0.37
- mucopolysaccharidosis type 4 · score 0.34
- Intellectual disability · score 0.12
- breast adenocarcinoma · score 0.10
- mean corpuscular volume · score 0.08
- mean reticulocyte volume · score 0.07
- hematocrit · score 0.06
- hemoglobin measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UL33-F1 | alphafold | PREDICTED | 91.89 | — |
Amino-acid sequence (140 residues)
MAVCIAVIAK ENYPLYIRST PTENELKFHY MVHTSLDVVD EKISAMGKAL VDQRELYLGL LYPTEDYKVY GYVTNSKVKF VMVVDSSNTA LRDNEIRSMF RKLHNSYTDV MCNPFYNPGD RIQSSRAFDN MVTSMMIQVC
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